Dr. Tran

nicholas.tran@bcm.edu

Nicholas Tran PhD, Principal Investigator

Dr. Tran is an Assistant Professor at Baylor College of Medicine in the Department of Molecular and Human Genetics. He received his Ph.D. from Washington University in St. Louis in Molecular Genetics and Genomics where he was mentored by Dr. Shiming Chen. He performed his postdoctoral research in Dr. Joshua Sanes’s lab at Harvard University.

Our research focuses on cell type-specific mechanisms underlying retinal ganglion cell degeneration in traumatic injury and diseases such as glaucoma. Ultimately, our work seeks to elucidate guiding principles of neuronal survival and axon regeneration that will serve to improve therapies for different forms of neurodegeneration within and beyond the retina.

Outside of the lab, he likes to spend time with family and friends. He enjoys cooking and exploring Houston's food scene. He's also a sci-fi nerd.

Justin D

justin.dhindsa@bcm.edu

Justin Dhindsa, Graduate Student

Justin is currently a 2nd-year graduate student in the Genetics & Genomics program and 4th year in the MSTP. He received his B.S. in Biology from Duke University in 2021.

He is interested in applying single-cell genomics to understanding the genetics of RGC development and optic neuropathy.

Justin likes to run, rockclimb, go to the gym, and cook.

Jeswin
Jeswin.@bcm.edu

jeswin.elizabethjames@bcm.edu

Jeswin Elizabeth James MS, Research Assistant

Jeswin received her Bachelor of Technology with Honors in Biotechnology and Biochemical Engineering from APJ Abdul Kalam Technological University. She then went on to earn her Masters in Biotechnology from Texas A&M.

She is broadly interested in neurodegenerative diseases, human genetics, translational neuroscience, and regenerative neuroscience.

Jeswin likes to spend time with family and friends, cook, go on road trips, go hiking, and go to church and fellowship.

Han
Han-Yin

han-yin.jeng@bcm.edu

Han-Yin Jeng MS, Graduate Student

Han-Yin grew up in Taiwan and earned her B.S. and M.S. degrees in Medical Laboratory Science and Biotechnology from Taipei Medical University. During her studies, she investigated drug mechanisms in lung adenocarcinoma. After graduation, she worked as a research assistant at the Research Center of Cell Therapy and Regeneration Medicine at Taipei Medical University, where she studied the immunoregulatory effects of mesenchymal stem cells (MSCs) on lung inflammation and developed Good Tissue Practice (GTP) protocols for producing cell products for cell therapy.

Han-Yin later moved to Houston to pursue a Ph.D. in the DDMT program at Baylor College of Medicine in the Tran Lab. Her current research focuses on elucidating the role of pro-inflammatory cytokines in retinal ganglion cell (RGC) regeneration and degeneration, using both 2D and 3D adult primary RGC and iPSC-derived RGC models, along with AAV and HDAd-based gene delivery systems.

Outside of the lab, Han-Yin likes to listen to podcasts about mysterious topics.

Grace
Grace

gcp3@rice.edu

Grace Park, Undergraduate Student

Grace is currently a third year student at Rice University majoring in Neuroscience.

She is interested in investigating the link between neuronal activity and resilience following optic nerve injury. She is seeking to optimize methodologies for precisely measuring cell activity levels so that they may be correlated with or against RGC resilience. Namely, she is evaluating the effectiveness of cyclic adenosine monophosphate (cAMP) biosensors in reflecting neuronal activity levels.

Grace enjoys going to concerts & museums, and playing music.

Austin
Austin

austin.pierce@bcm.edu

Austin Pierce MS, Research Assistant

Austin received his B.S. in Biology from Indiana University.

Austin is interested in studying the development of regenerative therapeutics.

In his free time, he likes to explore the Greater Houston area or stay in and binge shows.

Rhea
Rhea

rhea.ray@bcm.edu

Rhea Ray, Undergraduate Student

Rhea is a third-year student at Rice University majoring in Neuroscience and Social Policy Analysis.

She is interested in researching the selective vulnerability and resilience of Retinal Ganglion Cell types after Optic Nerve Injury, and specifically looks to investigate the effects of neuronal activity on alpha-RGC resilience. Through this relationship, she is working to elucidate the mechanism of Corticotropin-Releasing Hormone (CRH) and its ability to support RGC resilience.

In her free time, Rhea likes to play intramural flag football, learn languages, and solve puzzles.

Borna
Borna

borna.sarker@bcm.edu

Borna Sarker PhD, Postdoctoral Fellow

Borna received her BS in Biology from Trinity University and her MS in Biomedical Sciences at Texas A&M University. She went on to complete her PhD in Cell and Molecular Biology at The University of Texas at San Antonio.

Her research interests include understanding the contributions of neuroglial and neurovascular interactions to the pathogenesis and progression of central nervous system diseases, and how these dynamics can be targeted and modulated to find novel treatment regimens for retinopathies and neurodegenerative diseases.

Borna's hobbies include singing, reading, learning languages, jigsaw puzzles, and watching movies and TV.

Kancheng
Kancheng

kancheng.yin@bcm.edu

Kancheng Yin MS, Graduate Student

Kancheng attended UCSD for both her undergraduate and masters degrees. She is a 2nd year graduate student in the Genetics & Genomics program.

She's interested in understanding the mechanisms behind axon regeneration and leveraging them for potential therapies.

In her free time, Kancheng likes to crochet, sing karaoke, and hang out with her cat Kiki.

Lab Alumni

Justin Ma, PhD

Postdoctoral Fellow • 2023–2026

Current: Exploring industry opportunities

Tingkuan Chu, MS

Research Assistant • 2022–2024

Current: PhD student at Washington University in St. Louis