Single-cell atlas of the transcriptome and chromatin accessibility in the human retina
Jin Li, Jun Wang, Ignacio L. Ibarra, Xuesen Cheng, Malte D. Luecken, Jiaxiong Lu, Aboozar Monavarfeshani, Wenjun Yan, Yiqiao Zheng, Zhen Zuo, Samantha Lynn Zayas Colborn, Berenice Sarahi Cortez, Leah A. Owen, Brittney Wick, Xuan Bao, Jongsu Choi, Maximilian Haeussler, Nicholas M. Tran, Karthik Shekhar, Joshua R. Sanes, J. Timothy Stout, Shiming Chen, Yumei Li, Margaret M. DeAngelis, Fabian J. Theis & Rui Chen.
Nature Genetics. (2026)

Rare heterozygous missense variants in VSX2 are associated with retinal detachment
Daniel C. Brock^*, Justin S. Dhindsa^*, Yifan Chen, Vida Ravanmehr, Jonathan Mitchell, Fengyuan Hu, Xiaoyin Li, Likhita Nandigam, Quanli Wang, Kevin Wu, Jessica C. Butts, Hardeep S. Dhindsa, Benjamin J. Frankfort, Nicholas M. Tran, Slavé Petrovski & Ryan S. Dhindsa.
PLOS Genetics. (2026)
^* Equal contribution

Coordinated stimulation of axon regenerative and neurodegenerative transcriptional programs by ATF4 following optic nerve injury
Prashanth Somasundaram, Matthew Farley, Michael Rudy, Kevin Sigal, Alejandra Asencor, David Stefanoff, Maaz Shah, Pavan Goli, Joon Heo, Shuo Wang, Nicholas M. Tran & Thomas Watkins.
eLife. (2026)

Optic nerve injury impairs intrinsic mechanisms underlying electrical activity in a resilient retinal ganglion cell
Thomas E. Zapadka, Nicholas M. Tran & Jonathan B. Demb.
The Journal of Physiology. (2025)

Sample multiplexing for retinal single-cell RNA sequencing
Jian Ma, Tsz Kwong Chu, Monica Polo-Prieto, Young-Kwang Park, Yumei Li, Rui Chen, Graeme Mardon, Benjamin J. Frankfort & Nicholas M. Tran.
iScience. (2024)

Comprehensive single-cell atlas of the mouse retina
Jin Li, Jongsu Choi, Xuesen Cheng, Jian Ma, Sonal Pema, Joshua R. Sanes, Graeme Mardon, Benjamin J. Frankfort, Nicholas M. Tran, Yumei Li & Rui Chen.
iScience. (2024)

Temporal single-cell atlas of non-neuronal retinal cells reveals dynamic, coordinated multicellular responses to central nervous system injury
Idan Benhar, Jiarui Ding, Irene E. Whitney, Anne Jacobi, Michael Sud, Gergely Burging, Karthik Shekhar, Nicholas M. Tran, Chen Wang, Zhigang He, Joshua R. Sanes & Aviv Regev.
Nature Immunology. (2023)

Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells
Anne Jacobi^*, Nicholas M. Tran^*, Wenjun Yan, Idan Benhar, Feng Tian, Robert Schaffer, Zhigang He & Joshua R. Sanes.
Neuron. (2022)
^* Equal contribution

Optic nerve regeneration screen identifies multiple genes restricting adult neural repair
John A. Lindborg, Nicholas M. Tran, Danielle M. Chenette, Kathleen DeLuca, Yaowu Foli, Rathnam Kannan, Yasushi Sekine, Xiaofei Wang, Matthew S. Wollan, In-Jung Kim, Joshua R. Sanes & Stephen M. Strittmatter.
Cell Reports. (2021)

Mouse Retinal Cell Atlas: Molecular Identification of over Sixty Amacrine Cell Types
Wenjun Yan, Marc Laboulaye, Nicholas M. Tran, Irene E. Whitney, Idan Benhar & Joshua R. Sanes.
Journal of Neuroscience. (2020)

Single-Cell Profiles of Retinal Ganglion Cells Differing in Resilience to Injury Reveal Neuroprotective Genes
Nicholas M. Tran^*, Karthik Shekhar^*, Irene E. Whitney, Anne Jacobi, Idan Benhar, Guosong Hong, Wenjun Yan, Xian Adiconis, Michael E. Arnold, Jeannie M. Lee, Joshua Z. Levin, David Lin, Chen Wang, Charles M. Lieber, Aviv Regev, Zhigang He & Joshua R. Sanes.
Neuron. (2019)
^* Equal contribution

Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics
Karthik Shekhar^*, Sylvain W. Lapan^*, Irene E. Whitney^*, Nicholas M. Tran, Evan Z. Macosko, Marek Kowalczyk, Xian Adiconis, Joshua Z. Levin, James Nemesh, Melissa Goldman, Steven A. McCarroll, Connie L. Cepko, Aviv Regev & Joshua R. Sanes.
Cell. (2016)
^* Equal contribution